Answer: -What are we talking about? A toilet? A sink? Bathroom? Kitchen? Landscape drainage pipe? A funnel-shaped plunger, auger, stiff wire may be useful. Block any overflows with a wet rag when using the plunger. I have never had to use harsh chemicals, and that would be my last resort before the expense of calling a plumber. Keep your drains clean with regular maintenance. After your drain runs free: Put a few spoons of baking soda down your drain, add a cup of vinegar, wait 30 minutes and follow up with a gallon of boiling water. Just running hot tap water for a minute will help clear a drain, but don't try it in a toilet (you could crack the porcelain). -Shaklee has a non-polluting, biodegradable enzyme product called "Biodegreat!" that has no caustic fumes. You use a couple of teaspoons in each drain once a month. It eats the gunk in your pipes while you sleep. If your pipes are badly clogged, I'd apply it, let it sit overnight, then use a plunger to unclog. Reapply if needed. Once your pipes are clear, monthly applications should keep them that way. You can find a dealer in your area at www.shaklee.com.